Telomere attrition and inflammation: the chicken and the egg story

Abstract The challenge to improve human life span has progressed with the advent of health care services and technologies. This improvement poses a new an associated wave diseases pathologies that have not been observed or experienced. led rise in geriatric population who are currently facing challenges needs be addressed by research community. review focuses primarily on two mechanisms contributed aging pathologies: telomere attrition inflammatory insults. A strong interplay appears exist between inflammation, this could basis many increasing age. creates scientific dilemma as what comes first: inflammation. will enthuse reader underlying molecules inflammation their contribution aging.